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  1. Research

    Should chemoprophylaxis be a main strategy for preventing re-introduction of malaria in highly receptive areas? Sri Lanka a case in point

    Imported malaria cases continue to be reported in Sri Lanka, which was declared ‘malaria-free’ by the World Health Organization in September 2016. Chemoprophylaxis, a recommended strategy for malaria preventio...

    A. Rajitha Wickremasinghe, Renu Wickremasinghe, Hemantha D. B. Herath and S. Deepika Fernando

    Malaria Journal 2017 16:102

    Published on: 4 March 2017

  2. Research

    In vivo efficacy of top five surveyed Ghanaian herbal anti-malarial products

    Anti-malarial herbal preparations (HPs) continue to enjoy high patronage in Ghana despite reports that the artemisinin-based combination therapy (ACT), the recommended first choice for treatment of uncomplicat...

    Dennis Wilmot, Elvis Ofori Ameyaw, Daniel Amoako-Sakyi, Johnson Nyarko Boampong and Neils Ben Quashie

    Malaria Journal 2017 16:103

    Published on: 4 March 2017

  3. Review

    Evidence of metabolic mechanisms playing a role in multiple insecticides resistance in Anopheles stephensi populations from Afghanistan

    Malaria is endemic in most parts of Afghanistan and insecticide-based vector control measures are central in controlling the disease. Insecticide resistance in the main malaria vector Anopheles stephensi from Afg...

    Noor Halim Zahid Safi, Abdul Ali Ahmadi, Sami Nahzat, Seyyed Payman Ziapour, Seyed Hassan Nikookar, Mahmoud Fazeli-Dinan, Ahmadali Enayati and Janet Hemingway

    Malaria Journal 2017 16:100

    Published on: 3 March 2017

  4. Research

    The shape of the iceberg: quantification of submicroscopic Plasmodium falciparum and Plasmodium vivax parasitaemia and gametocytaemia in five low endemic settings in Ethiopia

    The widespread presence of low-density asymptomatic infections with concurrent gametocytes may be a stumbling block for malaria elimination. This study investigated the asymptomatic reservoir of Plasmodium falcip...

    Fitsum G. Tadesse, Lotus van den Hoogen, Kjerstin Lanke, Jodie Schildkraut, Kevin Tetteh, Abraham Aseffa, Hassen Mamo, Robert Sauerwein, Ingrid Felger, Chris Drakeley, Endalamaw Gadissa and Teun Bousema

    Malaria Journal 2017 16:99

    Published on: 3 March 2017

  5. Research

    Selections, frameshift mutations, and copy number variation detected on the surf 4.1 gene in the western Kenyan Plasmodium falciparum population

    Plasmodium falciparum SURFIN4.1 is a putative ligand expressed on the merozoite and likely on the infected red blood cell, whose gene was suggested to be under directional selection in...

    Jesse N. Gitaka, Mika Takeda, Masatsugu Kimura, Zulkarnain Md Idris, Chim W. Chan, James Kongere, Kazuhide Yahata, Francis W. Muregi, Yoshio Ichinose, Akira Kaneko and Osamu Kaneko

    Malaria Journal 2017 16:98

    Published on: 2 March 2017

  6. Research

    Molecular surveillance of artemisinin resistance falciparum malaria among migrant goldmine workers in Myanmar

    Artemisinin resistance has been reported in Greater Mekong Sub-region countries, including Myanmar. After discovery of artemisinin resistance marker (K13), molecular surveillance on artemisinin resistance in e...

    Myat Htut Nyunt, Bo Wang, Khin Myo Aye, Kyin Hla Aye, Jin-Hee Han, Seong-Kyun Lee, Kay Thwe Han, Ye Htut and Eun-Taek Han

    Malaria Journal 2017 16:97

    Published on: 1 March 2017

  7. Research

    Assessment of the utility of a symptom-based algorithm for identifying febrile patients for malaria diagnostic testing in Senegal

    Malaria rapid diagnostic tests (RDTs) enable point-of-care testing to be nearly as sensitive and specific as reference microscopy. The Senegal National Malaria Control Programme introduced RDTs in 2007, along ...

    Julie Thwing, Fatou Ba, Alou Diaby, Younouss Diedhiou, Assane Sylla, Guelaye Sall, Mame Birame Diouf, Alioune Badara Gueye, Seynabou Gaye, Medoune Ndiop, Moustapha Cisse, Daouda Ndiaye and Mady Ba

    Malaria Journal 2017 16:95

    Published on: 1 March 2017

  8. Research

    Assessing the impact of differences in malaria transmission intensity on clinical and haematological indices in children with malaria

    Malaria control interventions have led to a decline in transmission intensity in many endemic areas, and resulted in elimination in some areas. This decline, however, will lead to delayed acquisition of protec...

    Henrietta E. Mensah-Brown, James Abugri, Kwaku P. Asante, Duah Dwomoh, David Dosoo, Frank Atuguba, David J. Conway and Gordon A. Awandare

    Malaria Journal 2017 16:96

    Published on: 1 March 2017

  9. Research

    Acceptability of insecticide-treated clothing for malaria prevention among migrant rubber tappers in Myanmar: a cluster-randomized non-inferiority crossover trial

    Insecticide-treated clothing (ITC) has long been used for military and outdoor recreational purposes and there is substantial evidence to show that it can protect against arthropod biting. As a complementary v...

    Alison F. Crawshaw, Thae Maung Maung, Muhammad Shafique, Nyan Sint, Sarala Nicholas, Michelle S. Li, Arantxa Roca-Feltrer and Jeffrey Hii

    Malaria Journal 2017 16:92

    Published on: 28 February 2017

  10. Research

    Long-term acceptability, durability and bio-efficacy of ZeroVector® durable lining for vector control in Papua New Guinea

    This study examined the acceptability, durability and bio-efficacy of pyrethroid-impregnated durable lining (DL) over a three-year period post-installation in residential homes across Papua New Guinea (PNG).

    Joseph J. Kuadima, Lincoln Timinao, Laura Naidi, Anthony Tandrapah, Manuel W. Hetzel, Cyrille Czeher and Justin Pulford

    Malaria Journal 2017 16:93

    Published on: 28 February 2017

  11. Review

    Malaria parasite clearance

    Following anti-malarial drug treatment asexual malaria parasite killing and clearance appear to be first order processes. Damaged malaria parasites in circulating erythrocytes are removed from the circulation ...

    Nicholas J. White

    Malaria Journal 2017 16:88

    Published on: 23 February 2017

  12. Research

    Integrating malaria surveillance with climate data for outbreak detection and forecasting: the EPIDEMIA system

    Early indication of an emerging malaria epidemic can provide an opportunity for proactive interventions. Challenges to the identification of nascent malaria epidemics include obtaining recent epidemiological s...

    Christopher L. Merkord, Yi Liu, Abere Mihretie, Teklehaymanot Gebrehiwot, Worku Awoke, Estifanos Bayabil, Geoffrey M. Henebry, Gebeyaw T. Kassa, Mastewal Lake and Michael C. Wimberly

    Malaria Journal 2017 16:89

    Published on: 23 February 2017

  13. Research

    Change in Anopheles richness and composition in response to artificial flooding during the creation of the Jirau hydroelectric dam in Porto Velho, Brazil

    Anopheles mosquitoes are the only vectors of human malaria. Anopheles species use standing water as breeding sites. Human activities, like the creation of an artificial lake during the...

    Moreno S. Rodrigures, Elis P. Batista, Alexandre A. Silva, Fábio M. Costa, Verissimo A. S. Neto and Luiz Herman S. Gil

    Malaria Journal 2017 16:87

    Published on: 22 February 2017

  14. Research

    Developing global maps of insecticide resistance risk to improve vector control

    Significant reductions in malaria transmission have been achieved over the last 15 years with elimination occurring in a small number of countries, however, increasing drug and insecticide resistance threatens...

    Michael Coleman, Janet Hemingway, Katherine Ann Gleave, Antoinette Wiebe, Peter W. Gething and Catherine L. Moyes

    Malaria Journal 2017 16:86

    Published on: 21 February 2017

  15. Research

    Geographical distributions of African malaria vector sibling species and evidence for insecticide resistance

    Many of the mosquito species responsible for malaria transmission belong to a sibling complex; a taxonomic group of morphologically identical, closely related species. Sibling species often differ in several i...

    Antoinette Wiebe, Joshua Longbottom, Katherine Gleave, Freya M. Shearer, Marianne E. Sinka, N. Claire Massey, Ewan Cameron, Samir Bhatt, Peter W. Gething, Janet Hemingway, David L. Smith, Michael Coleman and Catherine L. Moyes

    Malaria Journal 2017 16:85

    Published on: 20 February 2017

  16. Case study

    Changing the policy for intermittent preventive treatment with sulfadoxine–pyrimethamine during pregnancy in Malawi

    The growing resistance of Plasmodium falciparum to sulfadoxine–pyrimethamine (SP) treatment for uncomplicated malaria led to a recommendation by the World Health Organization for the use of artemisinin-based comb...

    Chikondi A. Mwendera, Christiaan de Jager, Herbert Longwe, Kamija Phiri, Charles Hongoro and Clifford M. Mutero

    Malaria Journal 2017 16:84

    Published on: 20 February 2017

  17. Research

    Experimental hut evaluation of a novel long-lasting non-pyrethroid durable wall lining for control of pyrethroid-resistant Anopheles gambiae and Anopheles funestus in Tanzania

    A novel, insecticide-treated, durable wall lining (ITWL), which mimics indoor residual spraying (IRS), has been developed to provide prolonged vector control when fixed to the inner walls of houses. PermaNet® ITW...

    Robert Malima, Basiliana Emidi, Louisa A. Messenger, Richard M. Oxborough, Bernard Batengana, Wema Sudi, Sophie Weston, George Mtove, Joseph P. Mugasa, Franklin W. Mosha, Mark W. Rowland and William Kisinza

    Malaria Journal 2017 16:82

    Published on: 17 February 2017

  18. Research

    Local constraints to access appropriate malaria treatment in the context of parasite resistance in Cambodia: a qualitative study

    Despite emerging drug resistance in Cambodia, artemisinin-based combination therapy (ACT) is still the most efficacious therapy. ACT is available free of charge in the Cambodian public sector and at a subsidiz...

    Jesse Verschuere, Tom Decroo, Dara Lim, Jean-Marie Kindermans, Chea Nguon, Rekol Huy, Yasmine Alkourdi, Koen Peeters Grietens and Charlotte Gryseels

    Malaria Journal 2017 16:81

    Published on: 17 February 2017

  19. Research

    Diversity and distribution of avian malaria and related haemosporidian parasites in captive birds from a Brazilian megalopolis

    The role of zoos in conservation programmes has increased significantly in last decades, and the health of captive animals is essential to guarantee success of such programmes. However, zoo birds suffer from p...

    Carolina Romeiro Fernandes Chagas, Gediminas Valkiūnas, Lilian de Oliveira Guimarães, Eliana Ferreira Monteiro, Fernanda Junqueira Vaz Guida, Roseli França Simões, Priscila Thihara Rodrigues, Expedito José de Albuquerque Luna and Karin Kirchgatter

    Malaria Journal 2017 16:83

    Published on: 17 February 2017

  20. Research

    A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites

    The Plasmodium genome encodes for a number of 6-Cys proteins that contain a module of six cysteine residues forming three intramolecular disulphide bonds. These proteins have been well characterized at transmissi...

    Gourab Paul, Arunaditya Deshmukh, Inderjeet Kaur, Sumit Rathore, Surbhi Dabral, Ashutosh Panda, Susheel Kumar Singh, Asif Mohmmed, Michael Theisen and Pawan Malhotra

    Malaria Journal 2017 16:79

    Published on: 16 February 2017

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