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  1. Research

    Individuals living in a malaria-endemic area of Cameroon do not have an acquired antibody response to Plasmodium falciparum histidine-rich protein 2

    Diagnosis of Plasmodium falciparum is often based on detection of histidine-rich protein 2 (HRP2) in blood. Most HRP2-based assays have high sensitivity and specificity; however, authors have suggested that antib...

    Diane Wallace Taylor, Naveen Bobbili, Vedbar S. Khadka, Isabella A. Quakyi and Rose G. F. Leke

    Malaria Journal 2017 16:58

    Published on: 1 February 2017

  2. Research

    Malaria control and prevention towards elimination: data from an eleven-year surveillance in Shandong Province, China

    Shandong Province experienced a declining malaria trend of local-acquired transmission, but the increasing imported malaria remains a challenge. Therefore, understanding the epidemiological characteristics of ...

    Xiangli Kong, Xin Liu, Hong Tu, Yan Xu, Jianbing Niu, Yongbin Wang, Changlei Zhao, Jingxuan Kou and Jun Feng

    Malaria Journal 2017 16:55

    Published on: 31 January 2017

  3. Research

    Submicroscopic Plasmodium prevalence in relation to malaria incidence in 20 villages in western Cambodia

    Cambodia has seen a marked reduction in the incidence of Plasmodium falciparum over the past decade without a corresponding decline in Plasmodium vivax incidence. It is unknown to what extent local transmission i...

    Rupam Tripura, Thomas J. Peto, Christianne C. Veugen, Chea Nguon, Chan Davoeung, Nicola James, Mehul Dhorda, Richard J. Maude, Jureeporn Duanguppama, Krittaya Patumrat, Mallika Imwong, Lorenz von Seidlein, Martin P. Grobusch, Nicholas J. White and Arjen M. Dondorp

    Malaria Journal 2017 16:56

    Published on: 31 January 2017

  4. Research

    Severe malaria in Europe: an 8-year multi-centre observational study

    Malaria remains one of the most serious infections for travellers to tropical countries. Due to the lack of harmonized guidelines a large variety of treatment regimens is used in Europe to treat severe malaria.

    Florian Kurth, Michel Develoux, Matthieu Mechain, Denis Malvy, Jan Clerinx, Spinello Antinori, Ida E. Gjørup, Joaquím Gascon, Kristine Mørch, Emanuele Nicastri, Michael Ramharter, Alessandro Bartoloni, Leo Visser, Thierry Rolling, Philipp Zanger, Guido Calleri…

    Malaria Journal 2017 16:57

    Published on: 31 January 2017

  5. Research

    Severe Plasmodium vivax infection in Korea

    Although severe malaria by Plasmodium vivax has been increasingly reported, there are marked variations in the type and rate of the complications by geographic area. This is possibly because of the presence of co...

    Jae Hyoung Im, Hea Yoon Kwon, JiHyeon Baek, Seong Wook Park, Areum Durey, Kyung Hee Lee, Moon-Hyun Chung and Jin-Soo Lee

    Malaria Journal 2017 16:51

    Published on: 28 January 2017

  6. Research

    Effect of a short course of iron polymaltose on acquisition of malarial parasitaemia in anaemic Indonesian schoolchildren: a randomized trial

    Concern exists about the safety of iron supplementation given to individuals in malarious areas. The possible unfavourable impact of iron supplementation on malaria might be less when slow-release iron compoun...

    Margaretta A. Prasetyani, Quirijn de Mast, Robel Afeworki, Maria M. M. Kaisar, Difa Stefanie, Erliyani Sartono, Taniawati Supali and André J. van der Ven

    Malaria Journal 2017 16:50

    Published on: 28 January 2017

  7. Research

    Working towards consensus on methods used to elicit participant-reported safety data in uncomplicated malaria clinical drug studies: a Delphi technique study

    Eliciting adverse event (AE) and non-study medication data reports from clinical research participants is integral to evaluating drug safety. However, using different methods to question participants yields i...

    Nyaradzo Mandimika, Karen I. Barnes, Clare I. R. Chandler, Cheryl Pace and Elizabeth N. Allen

    Malaria Journal 2017 16:52

    Published on: 28 January 2017

  8. Research

    Health Impact Assessment of Indira Sagar Project: a paramount to studies on Water Development Projects

    Very limited studies on Health Impact Assessment (HIA) of Water Development Projects (WDP) in relation to mosquito-borne diseases have been carried out in India. The current study focuses on using HIA as a too...

    Anushrita, B. N. Nagpal, Neera Kapoor, Aruna Srivastava, Rekha Saxena, Shailendra Singh, Sanjeev Gupta, Sompal Singh, Kumar Vikram and Neena Valecha

    Malaria Journal 2017 16:47

    Published on: 26 January 2017

  9. Research

    Serology reveals heterogeneity of Plasmodium falciparum transmission in northeastern South Africa: implications for malaria elimination

    It is widely acknowledged that modifications to existing control interventions are required if South Africa is to achieve malaria elimination. Targeting indoor residual spraying (IRS) to areas where cases have...

    Joseph Biggs, Jaishree Raman, Jackie Cook, Khumbulani Hlongwana, Chris Drakeley, Natashia Morris, Ishen Serocharan, Eunice Agubuzo, Philip Kruger, Aaron Mabuza, Alpheus Zitha, Elliot Machaba, Maureen Coetzee and Immo Kleinschmidt

    Malaria Journal 2017 16:48

    Published on: 26 January 2017

  10. Research

    The impact of urbanization and population density on childhood Plasmodium falciparum parasite prevalence rates in Africa

    Although malaria has been traditionally regarded as less of a problem in urban areas compared to neighbouring rural areas, the risk of malaria infection continues to exist in densely populated, urban areas of ...

    Caroline W. Kabaria, Marius Gilbert, Abdisalan M. Noor, Robert W. Snow and Catherine Linard

    Malaria Journal 2017 16:49

    Published on: 26 January 2017

  11. Research

    Artemether-lumefantrine and liver enzyme abnormalities in non-severe Plasmodium falciparum malaria in returned travellers: a retrospective comparative study with quinine-doxycycline in a Portuguese centre

    Artemisinin-based therapy is the current standard treatment for non-severe malaria due to Plasmodium falciparum. The potential for asymptomatic liver toxicity of this therapy and its implication in clinical prac...

    André Silva-Pinto, Rogério Ruas, Francisco Almeida, Raquel Duro, André Silva, Cândida Abreu and António Sarmento

    Malaria Journal 2017 16:43

    Published on: 25 January 2017

  12. Research

    In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate

    Recently published data suggest that artemisinin derivatives and synthetic peroxides, such as the ozonides OZ277 and OZ439, have a similar mode of action. Here the cross-resistance of OZ277 and OZ439 and four ...

    Fabian Baumgärtner, Joëlle Jourdan, Christian Scheurer, Benjamin Blasco, Brice Campo, Pascal Mäser and Sergio Wittlin

    Malaria Journal 2017 16:45

    Published on: 25 January 2017

  13. Research

    Efficacy of text-message reminders on paediatric malaria treatment adherence and their post-treatment return to health facilities in Kenya: a randomized controlled trial

    Short Message Service (SMS) reminders have been suggested as a potential intervention for improving adherence to medications and health facility attendance.

    Ambrose O. Talisuna, Amos Oburu, Sophie Githinji, Josephine Malinga, Beatrice Amboko, Philip Bejon, Caroline Jones, Robert W. Snow and Dejan Zurovac

    Malaria Journal 2017 16:46

    Published on: 25 January 2017

  14. Research

    Response to fever and utilization of standby emergency treatment (SBET) for malaria in travellers to Southeast Asia: a questionnaire-based cohort study

    Guidelines in several European countries recommend standby emergency treatment (SBET) for travellers to regions with low or medium malaria transmission instead of continuous chemoprophylaxis: travellers are ad...

    Christof D. Vinnemeier, Camilla Rothe, Benno Kreuels, Marylyn M. Addo, Sabine Vygen-Bonnet, Jakob P. Cramer and Thierry Rolling

    Malaria Journal 2017 16:44

    Published on: 25 January 2017

  15. Research

    On the cytokine/chemokine network during Plasmodium vivax malaria: new insights to understand the disease

    The clinical outcome of malaria depends on the delicate balance between pro-inflammatory and immunomodulatory cytokine responses triggered during infection. Despite the numerous reports on characterization of ...

    Natália Satchiko Hojo-Souza, Dhelio Batista Pereira, Fernanda Sumika Hojo de Souza, Tiago Antônio de Oliveira Mendes, Mariana Santos Cardoso, Mauro Shugiro Tada, Graziela Maria Zanini, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara and Lilian Lacerda Bueno

    Malaria Journal 2017 16:42

    Published on: 24 January 2017

  16. Research

    Optimization of mosquito egg production under mass rearing setting: effects of cage volume, blood meal source and adult population density for the malaria vector, Anopheles arabiensis

    Anopheles arabiensis is one of the major malaria vectors that put millions of people in endemic countries at risk. Mass-rearing of this mosquito is crucial for strategies that use ster...

    Wadaka Mamai, Nanwintoum S. Bimbile-Somda, Hamidou Maiga, José Guillermo Juarez, Zaynab A. I. Muosa, Adel Barakat Ali, Rosemary Susan Lees and Jeremie R. L. Gilles

    Malaria Journal 2017 16:41

    Published on: 24 January 2017

  17. Research

    Recent uptake of intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine is associated with increased prevalence of Pfdhfr mutations in Bobo-Dioulasso, Burkina Faso

    The impact of sulfadoxine–pyrimethamine (SP) used as intermittent preventive treatment during pregnancy (IPTp-SP) on mutant parasite selection has been poorly documented in Burkina Faso. This study sought firs...

    Mamoudou Cisse, Gordon A. Awandare, Alamissa Soulama, Halidou Tinto, Marie-Pierre Hayette and Robert T. Guiguemdé

    Malaria Journal 2017 16:38

    Published on: 23 January 2017

  18. Research

    A(maize)ing attraction: gravid Anopheles arabiensis are attracted and oviposit in response to maize pollen odours

    Maize cultivation contributes to the prevalence of malaria mosquitoes and exacerbates malaria transmission in sub-Saharan Africa. The pollen from maize serves as an important larval food source for Anopheles mosq...

    Betelehem Wondwosen, Sharon R. Hill, Göran Birgersson, Emiru Seyoum, Habte Tekie and Rickard Ignell

    Malaria Journal 2017 16:39

    Published on: 23 January 2017

  19. Research

    Health worker adherence to malaria treatment guidelines at outpatient health facilities in southern Malawi following implementation of universal access to diagnostic testing

    Appropriate diagnosis and treatment are essential for reducing malaria mortality. A cross-sectional outpatient health facility (HF) survey was conducted in southern Malawi from January to March 2015 to determi...

    Ruth J. Namuyinga, Dyson Mwandama, Dubulao Moyo, Austin Gumbo, Peter Troell, Miwako Kobayashi, Monica Shah, Andrew Bauleni, Jodi Vanden Eng, Alexander K. Rowe, Don P. Mathanga and Laura C. Steinhardt

    Malaria Journal 2017 16:40

    Published on: 23 January 2017

  20. Research

    Performance of loop-mediated isothermal amplification (LAMP) for the diagnosis of malaria among malaria suspected pregnant women in Northwest Ethiopia

    Malaria is a major public health problem and an important cause of maternal and infant morbidity in sub-Saharan Africa, including Ethiopia. Early and accurate diagnosis of malaria with effective treatment is t...

    Banchamlak Tegegne, Sisay Getie, Wossenseged Lemma, Abu Naser Mohon and Dylan R. Pillai

    Malaria Journal 2017 16:34

    Published on: 19 January 2017

  21. Research

    Heterogeneity of G6PD deficiency prevalence in Mozambique: a school-based cross-sectional survey in three different regions

    Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked hereditary enzymatic abnormality that affects more than 400 million people worldwide. Most deficient individuals do not manifest any symptoms;...

    Beatriz Galatas, Lurdes Mabote, Wilson Simone, Gloria Matambisso, Lidia Nhamussua, María del Mar Mañú-Pereira, Clara Menéndez, Francisco Saute, Eusebio Macete, Quique Bassat, Pedro Alonso and Pedro Aide

    Malaria Journal 2017 16:36

    Published on: 19 January 2017

  22. Research

    Effects of Plasmodium falciparum infection on umbilical artery resistance and intrafetal blood flow distribution: a Doppler ultrasound study from Papua New Guinea

    Doppler velocimetry studies of umbilical artery (UA) and middle cerebral artery (MCA) flow help to determine the presence and severity of fetal growth restriction. Increased UA resistance and reduced MCA pulsa...

    Maria Ome-Kaius, Stephan Karl, Regina Alice Wangnapi, John Walpe Bolnga, Glen Mola, Jane Walker, Ivo Mueller, Holger Werner Unger and Stephen John Rogerson

    Malaria Journal 2017 16:35

    Published on: 19 January 2017

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