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Figure 2 | Malaria Journal

Figure 2

From: Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria

Figure 2

Atovaquone (ATV) in P. falciparum cytochrome b active site. A: Atovaquone built and docked using HyperChem release 6, in the active site of a model of P. falciparum cytochrome B. Homology model prepared using the structure of the chicken enzyme [14] with the aid of the SWISS-MODEL Protein Modelling Server and observed in the Swiss Model Viewer [15]. B: As A, with active site tyrosine268 replaced by asparagine.

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Malaria Journal

ISSN: 1475-2875

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