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Table 1 In vitro sensitivity of isolate NGATV01 and strain K1 to standard antimalarial drugs with standard deviations (nmol/L).

From: Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria

Drug NGATV01 K1 Resistance Cut-off*
  Mean IC 50 ± SD Mean IC 50 ± SD  
Chloroquine 9.54 ± 1.18 133.29 ± 30.12 100
Mefloquine 24.14 ± 5.20 8.55 ± 0.29 20
Pyrimethamine 16012.80 ± 2643.55 8082.84 ± 1202.69 100
Atovaquone 1888.15 ± 106.65 2.41 ± 1.01 20
Proguanil 4205.50 ± 716.99 10239.94 ± 843.51 not determined
Dihydroartemisinin 2.39 ± 0.07 1.26 ± 0.46 not determined
  1. Drug assay was performed at 1 % parasitaemia and 1 % haematocrit. Experiment was repeated twice in duplicate.* Cut-off points for resistance as previously reported [16, 17, 6]