Table 7 Number of isolates clustered according to sensitivity to each drug and corresponding pfcrt and pfmdr1 genotypes
From: Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand
Drug | Pfcrt | Pfmdr1 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
76K | 76T | 76KT | 86N | 86Y | 86NY | 1042N | 1042D | 1042ND | 1246D | 1246Y | 1246DY | ||
CQ | Total | ||||||||||||
S | 2 | 2 | 0 | 0 | 1 | 1 | 0 | 2 | 0 | 0 | 2 | 0 | 0 |
R | 50 | 0 | 43 | 7 | 30 | 11 | 9 | 43 | 4 | 0 | 46 | 1 | 3 |
MF | |||||||||||||
S | 35 | 2 | 27 | 6 | 2 | 11 | 7 | 29 | 3 | 0 | 32 | 1 | 2 |
R | 17 | 0 | 16 | 1 | 29 | 1 | 2 | 16 | 1 | 0 | 16 | 0 | 1 |
QUIN | |||||||||||||
S | 52 | 2 | 43 | 7 | 31 | 12 | 9 | 45 | 4 | 0 | 48 | 1 | 3 |
R | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
AMQ | |||||||||||||
S | 13 | 0 | 9 | 4 | 9 | 2 | 2 | 13 | 0 | 0 | 12 | 0 | 1 |
R | 18 | 2 | 13 | 3 | 7 | 4 | 7 | 15 | 0 | 0 | 15 | 1 | 2 |