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Table 7 Number of isolates clustered according to sensitivity to each drug and corresponding pfcrt and pfmdr1 genotypes

From: Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand

Drug   Pfcrt Pfmdr1
76K 76T 76KT 86N 86Y 86NY 1042N 1042D 1042ND 1246D 1246Y 1246DY
CQ Total             
S 2 2 0 0 1 1 0 2 0 0 2 0 0
R 50 0 43 7 30 11 9 43 4 0 46 1 3
MF              
S 35 2 27 6 2 11 7 29 3 0 32 1 2
R 17 0 16 1 29 1 2 16 1 0 16 0 1
QUIN              
S 52 2 43 7 31 12 9 45 4 0 48 1 3
R 0 0 0 0 0 0 0 0 0 0 0 0 0
AMQ              
S 13 0 9 4 9 2 2 13 0 0 12 0 1
R 18 2 13 3 7 4 7 15 0 0 15 1 2
  1. (CQ – chloroquine; MF – mefloquine; QUIN – quinine; AMQ – amodiaquine; S – sensitive; R – resistant; 76KT, 86NY, 1042ND and 1246DY – mixed infections; shaded boxes indicate the two cases where there was a significant association between the presence of a particular marker and drug sensitivity: pfcrt 76T/CQR, P = 0.001 and pfmdr1 86N/MFR, P < 0.001)