Cellular responses to Plasmodium falciparum erythrocyte membrane protein-1: use of relatively conserved synthetic peptide pools to determine CD4 T cell responses in malaria-exposed individuals in Benin, West Africa

Table 2 CD4 T cell proliferation to three pools of relatively conserved peptides of PfEMP-1

Pools of peptides	Mean CD4 T cell proliferation (Log₁₀)
Pools of peptides	Benin donors	UK controls	P value
DBLα (pool 1)	2.47 ± 0.15 ^1] (24)^2]	1.94 ± 0.18 (24)	P = 0.025
CIDRα + DBLβ-δ (pool 2)	2.47 ± 0.14 (23)	2.02 ± 0.20 (21)	P = 0.062
Exon 2 (pool 3)	2.44 ± 0.15 (24)	1.94 ± 0.20 (22)	P = 0.045

^1] Standard error of the Log₁₀ mean of dividing CD4 T cells in triplicate wells as determined by a flow cytometric assay described in Materials and Methods ^2] Total number of donors tested

ISSN: 1475-2875