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Table 3 Distribution of tandem repeat variants at DHFR and DHPS in field isolates

From: Molecular epidemiology of Plasmodium vivax anti-folate resistance in India

DHFR

Regions (%)

Total N (%)

Repeat Type

Delhi

Nadiad

Panna

Chennai

Kamrup

 

Type 1

54.54

0

11.76

0

0

8 (11.26)

Type 2

36.34

100

76.47

100

100

60 (84.5)

Type 3

9.09

0

0

0

0

1 (1.4)

Type 4

0

0

11.76

0

0

2 (2.81)

Total (N)

11

3

17

19

21

71

DHPS

Type A

10

10

0

5

21.05

9.27

Type B

90

85

83.34

90

26.31

75.25

Type C

0

0

5.55

5

0

 

Type D

0

5

5.55

0

15.79

5.15

Type E

0

0

0

0

10.52

2.06

Type F

0

0

0

0

10.52

2.06

Type G

0

0

5.55

0

10.52

3.09

Type H

0

0

0

0

5.26

1.03

Total (N)

20

20

18*

20

19*

97

  1. *: DNA sequences of tandem repeat region was not good in some isolates and therefore not included in analysis of tandem repeats