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Table 2 Age-adjusted IRR for the association between total IgG level with clinical malaria

From: Antibody levels to multiple malaria vaccine candidate antigens in relation to clinical malaria episodes in children in the Kasena-Nankana district of Northern Ghana

Antibody Antigen Crude IRR (95%CI) IRR adjusted for age
(95%CI)
P-value for adjusted IRR
IgG GLURP-R0 0.76 (0.67, 0.86) 0.85 (0.75, 0.96) 0.01
  GLURP-R2 0.65 (0.55, 0.78) 0.77 (0.65, 0.91) <0.01
  MSP1-3D7 0.72 (0.61, 0.85) 0.79 (0.69, 0.91) <0.01
  MSP1-FVO 0.81 (0.63, 1.06) 0.73 (0.58, 0.93) 0.01
  MSP3-3D7 0.75 (0.63, 0.89) 0.86 (0.74, 1.01) 0.06
  AMA1-3D7 0.72 (0.63, 0.82) 0.80 (0.71, 0.91) <0.01
  AMA1-FVO 0.72 (0.62, 0.83) 0.81 (0.71, 0.93) <0.01
  AMA1-LR32 0.74 (0.64, 0.85) 0.85 (0.74, 0.96) 0.01
  EBA-175 0.66 (0.56, 0.78) 0.81 (0.68, 0.97) 0.02
  LSA-1 0.79 (0.64, 0.98) 0.89 (0.73, 1.09) 0.26
  1. IRRs indicate the ratio of malaria incidence rates associated with a twofold increase in antibody level