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Table 1 List of important differentially expressed probes after administration of AQ in murine Liver.

From: A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine

Spot labels Fold Change Gene Name/Description GO : Biological function
11544 2.27 TAP binding protein antigen processing
20523 2.73 RAB39B, member RAS oncogene family GTP binding
18680 2.49 Neogenin ATP binding
11260 2.18 ATPase, Ca++ transporting, plasma membrane 1 ATP binding
12910 2.20 Dihydropyrimidinase-like 5 axon guidance
18325 3.18 Calcium channel, voltage-dependent, L type, alpha 1D subunit calcium channel activity
9921 3.51 Ankyrin repeat domain 6 DNA binding
18064 6.11 GATA binding protein 2 DNA binding
20032 2.51 Parathyroid hormone receptor 1 G-protein coupled receptor activity
12886 3.62 Transmembrane protein with EGF-like and two follistatin-like domains 1 growth factor activity
21365 3.33 Solute carrier family 38, member 1 L-glutamine transport
492 6.38 DNA segment, Chr 5, Wayne State University 178, expressed phospholipid biosynthesis
22462 -4.53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 ATP-dependent helicase activity
10941 -2.32 Calcium channel, voltage-dependent, L type, alpha 1C subunit calcium channel activity
2989 -2.69 Nucleoporin 153 DNA binding
22225 -4.12 Suppressor of variegation 4-20 homolog 1 (Drosophila) histone lysine N-methyltransferase activity
15707 -2.09 Lipoma HMGIC fusion partner-like 2 metabolism
9653 -2.55 GCN5 general control of amino acid synthesis-like 2 (yeast) N-acetyltransferase activity
7818 -2.15 Nuclear receptor subfamily 3, group C, member 2 transcription factor activity
  1. Fold change (FC) >2(Up-regulated) and FC<-2 (Down-regulated) and P < 0.01.