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Table 4 List of genes with their description and expression results by Q-PCR and microarray following treatment with AQ and SP in murine liver.

From: A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine

Gene Symbol Gene Name/Description Q-PCR fold change Microarray Result Up regulated(▲)/Down regulated ()
ADRA1B Adrenergic receptor, alpha 1b -6
CYP1A2 Cytochrome P450, family 1, subfamily a, polypeptide 2 -6
CYP2E1 Cytochrome P450, family 2, subfamily e, polypeptide 1 -5
SC4MOL Sterol-C4-methyl oxidase-like -4
H2DM Histocompatibility 2, class II, 1.2
RAC RAS-related C3 botulinum -1.8
MCM4 Minichromosome maintenance deficient 4 homolog 5
VKORC Vitamin K epoxide reductase complex, -1.5
SC5D Sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog 7
ADH1 Alcohol dehydrogenase 1 (class I) 4.8
GADD45 Growth arrest and DNA-damage-inducible 45 gamma 3.2
UGT2B1 UDP glucuronosyltransferase 2 family, polypeptide B1 5
MCM5 Minichromosome maintenance deficient 5 homolog 2.5
GCGR Glucagon receptor 8
  1. Note the direction similarity among Q-PCR and microarray findings for gene expression results.