| |
Paracetamol-group*
|
Placebo-group*
|
OR with confidence interval**
|
|---|
|
Day 0
|
100% (167/167)
|
100% (171/171)
| |
|
Day 7
|
93.3% (152/163)
|
87.5% (147/168)
|
0.51 (0.21 - 1.15)
|
|
Day 14
|
84.4% (133/147)
|
79.6% (131/144)
|
0.72 (0.40 - 1.28)
|
|
Day 21
|
77.0% (115/126)
|
75.1% (118/125)
|
0.87 (0.52 - 1.43)
|
|
Day 28
|
73.6% (108/113)
|
71.9% (111/116)
|
0.89 (0.56 - 1.41)
|
|
Day 35
|
72.8% (97/98)
|
70.5% (102/104)
|
0.87 (0.55 - 1.37)
|
- The adequate clinical and parasitological response (ACPR) rates in the two treatment groups (see text):
- *) Cumulative percentages of children with ACPR during follow-up. The number of children with ACPR/total number of children is given in parenthesis (on day 7 children admitted to hospital on day 0 and children with early treatment failure are included in the denominator).
- **) Cumulative odds ratio of having ACPR in the group treated with placebo in relation to the paracetamol-group (Mantel-Haenszel weighted odds ratio, 95% confidence interval in brackets).
