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Table 3 Intention to treat analysis of the effect of treatment with chloroquine 25 mg/kg

From: Paracetamol versus placebo in treatment of non-severe malaria in children in Guinea-Bissau: a randomized controlled trial

  Paracetamol-group* Placebo-group* OR with confidence interval**
Day 0 100% (167/167) 100% (171/171)  
Day 7 93.3% (152/163) 87.5% (147/168) 0.51 (0.21 - 1.15)
Day 14 84.4% (133/147) 79.6% (131/144) 0.72 (0.40 - 1.28)
Day 21 77.0% (115/126) 75.1% (118/125) 0.87 (0.52 - 1.43)
Day 28 73.6% (108/113) 71.9% (111/116) 0.89 (0.56 - 1.41)
Day 35 72.8% (97/98) 70.5% (102/104) 0.87 (0.55 - 1.37)
  1. The adequate clinical and parasitological response (ACPR) rates in the two treatment groups (see text):
  2. *) Cumulative percentages of children with ACPR during follow-up. The number of children with ACPR/total number of children is given in parenthesis (on day 7 children admitted to hospital on day 0 and children with early treatment failure are included in the denominator).
  3. **) Cumulative odds ratio of having ACPR in the group treated with placebo in relation to the paracetamol-group (Mantel-Haenszel weighted odds ratio, 95% confidence interval in brackets).