Paracetamol versus placebo in treatment of non-severe malaria in children in Guinea-Bissau: a randomized controlled trial

Table 4 Per protocol analysis of the effect of treatment with chloroquine 25 mg/kg

The adequate clinical and parasitological response (ACPR) rates in the two treatment groups (see text):
Excluded due to violation of the protocol: In the paracetamol group 2 and 3 children were treated
outside the study on day 21 and day 28, respectively. In the placebo-group 3 children were admitted to hospital on the day of inclusion and 1 child was treated outside the study on each of the days 21 and 35.
*) Cumulative percentages of children with ACPR during follow-up. The number of children with ACPR/total number of children is given in parenthesis (on day 7, children with early treatment failure are included in the denominator).
**) Cumulative odds ratio of having ACPR in the group treated with placebo in relation to the paracetamol-group (Mantel-Haenszel weighted odds ratio, 95% confidence interval in brackets).

ISSN: 1475-2875