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Table 1 Ranges of physiochemical properties of quinoline methanols investigated in this study.

From: Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice

Parameter Range
MW 324-475
cLogD (PP) 1.0-5.2
cLogD (ACD) -2.3-3.1
PSA (Å2) 36-104
LogP 0.4-3.7
# FRBs 3-11
# HBDs 1-5
# HBAs 3-7