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Table 4 Proportion (%) of prozone for Paracheck-Pf according to different denominators, 95% binomial confidence intervals (CI) within brackets

From: Prozone in malaria rapid diagnostics tests: how many cases are missed?

Category

Number

% of patients suspected of malaria

% of P. falciparum positive patients

% of samples with high parasitaemia

Patients suspected of malaria

(1 sample per patient included)

7,543

100

  

Samples positive for P. falciparum

873

11.6

(10.86-12.32)

100

 

Samples scored as 4+ or 5 + (MoH semi-quantitative scale)

410

5.4

(4.93-5.97)

47.0

(43.61-50.34)

 

Samples with a high parasitaemia (parasite density ≥ 4%)

92

1.2

(0.98-14.9)

10,5

(8,58-12,77)

100

Number of samples available for prozone testing

76

-

-

-

Negative, faint or weak HRP-2 test lines *

29

0.5

(0.32-0.64)

4.0

(2.81-5.53)

38.0

(28.12-48.76)

Negative or faint HRP-2 test lines *

8

0.1

(0.06-0.24)

1.2

(0.55-2.10)

10.9

(5.34-19.08)

Negative HRP-2 test lines *

3

0.05

(0.01-0.14)

0.5

(0.12-1.17)

4.4

(1.20-10.76)

  1. * Line intensity for undiluted samples
  2. Proportions calculated according to Table 2, corrected for the number of samples that were not available for prozone testing (n = 16).