Skip to main content

Table 5 Characteristics of P. falciparum samples that were prozone positive or negative for Paracheck-Pf

From: Prozone in malaria rapid diagnostics tests: how many cases are missed?

   Samples with high parasitaemia (parasite density ≥ 4%)
   Prozone positive Prozone negative Total p = *
   n = 29 n = 47 n = 76  
Demographic and clinical data (expressed as % of total)
   Patients (n= 76) Children < 5 years (n = 53) 82.8 61.7 69.8 NS
  Children ≥ 5 years (n = 14) 10.3 23.4 18.4 NS
  Adults (> 14 years) (n = 9) 6.9 14.9 11.8  
   Gender ratio (n = 74) Male/female 40.7 57.4 51.4 NS
   Presenting symptoms Fever (n = 64) 96.3 97.3 96.9 NS
  Cough (n = 59) 50.0 11.4 27.1 0.002
  Vomiting (n = 60) 28.0 45.7 38.3 NS
  Diarrhoea (n = 60) 28.0 45.7 30.0 NS
   Clinical signs of severity At least one (n = 60) 64.0 48.6 55.0 NS
   Laboratory sign of severity Haemoglobin < 5 g/dl (n = 76) 20.7 6.4 11.8 NS
   Signs of severity At least one clinical or laboratory (n = 61) 69.2 54.3 60.7 NS
Laboratory values (expressed as median and 95% CI)
   Parasite density in % (n = 76) Median 8.0 6.9 6.9 NS
  Range 4.0-28.7 4.2-22.3 4.0-28.7  
   Hemoglobin level (g/dl) (n = 76) Median 7.2 9.0 8.3 0.0074
  Range 2.9-12.5 2.5-13.3 2.5-13.3  
   RBC count (× 109/l) (n = 76) Median 3.1 3.8 3.4 0.0131
  Range 1.1-5.3 0.9-5.3 0.9-5.3  
   Platelet count (× 106/l) (n = 76) Median 74 90 86 NS
  Range 12-488 13-390 12-390  
   WBC count (× 106/l) (n = 76) Median 10.4 10.1 10.2 NS
  Range 4.4-19.9 3.2-27.6 3.2-27.6  
  1. * NS = not significant