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Table 3 Sensitivity, specificity, positive predictive value and negative predictive value of RDTs and microscopy versus real-time PCR as gold standard

From: Real-time PCR assay and rapid diagnostic tests for the diagnosis of clinically suspected malaria patients in Bangladesh

Method

Test

Sensitivity (95% CI)

Specificity (95% CI)

PPV (95% CI)

NPV (95%CI)

Kappa (k)

Paracheck

Pure and mixed Pf

97.1 (93.3-99)

96.4 (92.4-98.7)

96.5 (92.5-98.7)

97 (93.2-99)

0.94

Falcivax

Pure and mixed Pf

97.6 (94.1-99.4)

95.8 (91.6-98.3)

96 (91.8-98.4)

97.6 (93.9-99.3)

0.94

Onsite Pf

Pure and mixed Pf

94.1 (89.4-97.1)

97.6 (94-99.3)

97.6 (93.9-99.3)

94.3 (89.7-97.2)

0.92

Onsite Pf/Pv

Pure and mixed Pf

92.9 (88-96.3)

98.8 (95.8-99.9)

98.8 (95.6-99.8)

93.3 (88.5-96.5)

0.92

Microscopy

Pure and mixed Pf

97.6 (94.1-99.4)

97 (93.2-99)

97.1 (93.3-99)

97.6 (94-99.3)

0.95

Falcivax

Pure and mixed Pv

76.9 (56.4-91)

100 (98.8-100)

100 (83.2-100)

98.1 (95.9-99.3)

0.86

Onsite Pf/Pv

Pure and mixed Pv

76.9 (56.4-91)

99 (97.2-99.8)

87 (66.4-97.2)

98.1 (95.9-99.3)

0.80

Microscopy

Pure and mixed Pv

76.9 (56.4-91)

99.7 (98.2-100)

95.2 (76.2-99.9)

98.1 (95.8-99.3)

0.84

  1. (PPV = Positive predictive value, NPV = Negative predictive value)