Design of a variant surface antigen-supplemented microarray chip for whole transcriptome analysis of multiple Plasmodium falciparum cytoadherent strains, and identification of strain-transcendent rif and stevor genes

Table 3 Summary of strain-transcendent Stevors found in at least three out of 3D7, HB3, Dd2 and IT

3D7		HB3	Dd2	IT	Pairwise alignment score¹
Gene ID	Found in F.I.²	Gene ID	Gene ID	Gene ID	3D7- HB3	3D7- Dd2	HB3 - Dd2	IT- 3D7	IT- HB3	IT- Dd2
SteA_MAL13P1.7		HB3steA_14	/	IT4steA_11	99			87	87
SteB_PFD0125c		HB3steB_p18³	Dd2steB_18	IT4steB_01	99	93	91	99	93	92
SteB_t_PFB0955w⁴	yes	HB3steB_p26	/	IT4steB_14	98			99	99
SteB_p_PF10_0009		HB3steB_p20	Dd2steB_p29	IT4steB_p31	98	98	98	88	88	88
SteA_p_PFA0705c	yes	HB3steA_p23	Dd2steA_p31	/	99	96	98

¹Stevors with >90% amino acid identity between at least one pair of strains plus >80% amino acid identity between at least 2 other pairs of strains are shown.
²F.I: Brazilian field isolates [45]
³p=pseudogene: one or more stop codons or frameshifts within the sequence.
⁴t=truncated gene:part of the gene sequence is missing, possibly due to incomplete sequencing.

ISSN: 1475-2875