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Table 1 Comparison of the two treatment groups at inclusion

From: Comparative study of the efficacy and tolerability of dihydroartemisinin - piperaquine - trimethoprim versus artemether - lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroon, Ivory Coast and Senegal

 

DPT

AL

p*

Numbers

206

197

 

Sex M, n (%)

97 (47.1)

93 (47.2)

0.921

   F, n (%)

109 (52.9)

104 (52.8)

 

Mean age (SD) years

15.51 (12.64)

15.58 (11.91)

0.958

Min - Max

2 - 60

2 - 62

 

[2 - 5], n (%)

36 (17.5)

30 (15.2)

 

[5 - 15], n (%)

87 (42.2)

85 (43.1)

 

[15-62], n (%)

83 (40.3)

82 (41.6)

 

Mean temperature (SD) °C

38.73 (0.96)

38.58 (1.03)

0.134

Min - Max

35.5 - 41.0

35.2 - 41.4

 

< 37.5, n (%)

11 (5.3)

15 (7.6)

 

[37.5 - 38.5], n (%)

63 (30.6)

77 (39.1)

 

[38.5 - 41.4], n (%)

132 (64.1)

105 (53.3)

 

Median parasitaemia tpz/μl

13225

13400

0.934**

Min - Max

1000 - 255000

1040 - 187500

 

Gametocyte carrier rate, n (%)

3 (1.5)

0 (0)

0.249§

Mean ASAT (SD) IU/l

30.59 (21.71)

31.36 (18.99)

0.705

Min - Max

5-165

7-134

 

Mean ALAT (SD) IU/l

25.9 (20.61)

27.98 (16.20)

0.262

Min - Max

4-235

4-121

 

Mean creatinine (SD) mg/l

8.28 (2.39)

8.26 (2.43)

0.924

Min - Max

3-20

4-20

 

Mean bilirubin (SD) mg/l

9.57 (7.49)

10.88 (11.00)

0.162

Min - Max

2-59

2-85

 

Mean haemoglobin (SD) g/dl

10.60 (1.81)

10.80 (1.85)

0.289

Min - Max

5.8-15.1

5.1-16.8

 
  1. * t test for independent samples **Mann-Whitney test § Fisher's exact test.