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Table 6 Changes in individuals' biochemical indices used to assess tolerability

From: Comparative study of the efficacy and tolerability of dihydroartemisinin - piperaquine - trimethoprim versus artemether - lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroon, Ivory Coast and Senegal

Parameters DPT AL P**
  D1 D7 D1-D7 p* D1 D7 D1-D7 p*  
ASAT (SD) IU/l 30.53 (21.79) 28.83 (10.9) 1.7 (21.87) 0.271 31.25 (18.81) 32.69 (21.9) -1.44 (28.52) 0.492 0.223
ALAT (SD) IU/l 25.75 (20.46) 25.74 (12.51) 0.01 (20.77) 0.997 28.32 (16.46) 28.63 (17.82) -0.31 (23.94) 0.861 0.888
Creatinine (SD) mg/l 8.31 (2.39) 8.15 (2.46) 0.16 (2.59) 0.400 8.31 (2.46) 8.37 (2.47) -0.06 (2.88) 0.799 0.430
Bilirubin (SD) mg/l 9.52 (7.56) 7.68 (4.11) 1.84 (8.74) 0.003 10.75 (11.03) 7.71 (3.69) 3.04 (11.68) 0.000 0.245
  1. *paired t test.
  2. ** t test for independent samples comparing drop within individuals'values in DPT and AL groups.