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Table 6 Changes in individuals' biochemical indices used to assess tolerability

From: Comparative study of the efficacy and tolerability of dihydroartemisinin - piperaquine - trimethoprim versus artemether - lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroon, Ivory Coast and Senegal

Parameters DPT AL P**
  D1 D7 D1-D7 p* D1 D7 D1-D7 p*  
ASAT
(SD) IU/l
30.53
(21.79)
28.83
(10.9)
1.7
(21.87)
0.271 31.25
(18.81)
32.69
(21.9)
-1.44
(28.52)
0.492 0.223
ALAT
(SD) IU/l
25.75
(20.46)
25.74
(12.51)
0.01
(20.77)
0.997 28.32
(16.46)
28.63
(17.82)
-0.31
(23.94)
0.861 0.888
Creatinine
(SD) mg/l
8.31
(2.39)
8.15
(2.46)
0.16
(2.59)
0.400 8.31
(2.46)
8.37
(2.47)
-0.06
(2.88)
0.799 0.430
Bilirubin
(SD) mg/l
9.52
(7.56)
7.68
(4.11)
1.84
(8.74)
0.003 10.75
(11.03)
7.71
(3.69)
3.04
(11.68)
0.000 0.245
  1. *paired t test.
  2. ** t test for independent samples comparing drop within individuals'values in DPT and AL groups.