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Table 1 Comparison of the two treatment groups at inclusion

From: Multicentric assessment of the efficacy and tolerability of dihydroartemisinin-piperaquine compared to artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa

 

DP

AL

p*

Numbers

197

187

 

Sex

   

   M, n (%)

97 (49.2)

93 (47.2)

0.923**

   F, n (%)

100 (50.8)

94 (52.8)

 

Mean age (SD) years

15.64 (14.22)

13.48 (12.64)

0.117

[2 - 5[, n (%)

34 (17.3)

44 (23.7)

 

[5 - 15[, n (%)

92 (46.7)

83 (44.6)

 

[15-77], n (%)

71 (36.0)

59 (31.7)

 

Mean temperature (SD) °C

38.42 (0.64)

38.43 (0.73)

0.887

[37.5 - 38.5[, n (%)

114 (57.9)

113 (60.4)

 

[38.5 - 41.0], n (%)

83 (42.1)

74 (39.6)

 

Median parasitaemia tpz/μl

10840

16000

0.546§

Min - Max

1000 - 200000

1000 - 200000

 

Gametocyte carrier rate, n (%)

8 (4.1)

6 (3.2)

0.649**

Mean AST (SD) IU/l

26.64 (15.53)

31.1 (29.08)

0.065

Mean ALT (SD) IU/l

18.71 (12.71)

24.06 (36.63)

0.061

Mean creatinin (SD) mg/l

6.79 (2.41)

6.76 (2.47)

0.915

Mean bilirubin (SD) mg/l

10.43 (7.21)

11.4 (8.65)

0.236

Mean haemoglobin (SD) g/dl

10.79 (2.06)

10.67 (2.12)

0.575

  1. *Independent samples t test **Pearson's Chi-2 test §Mann-Whitney test
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Malaria Journal

ISSN: 1475-2875

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