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Table 1 n vitro anti-plasmodial activity of plant extracts against K1 strain of P. falciparum isolate

From: Anti-malarial activity of Holarrhena antidysenterica and Viola canescens, plants traditionally used against malaria in the Garhwal region of north-west Himalaya

Sl. No.

Plant extract

Anti-plasmodial activity (IC50μg/ml)

Cytotoxity IC50(μg/ml)

Selectivity Indexes

  

A

B

 

A

B

1.

HA-1

25

22

51.2

2

2.3

2.

HA-2

5.9

5.5

88.9

3.3

16

3.

HA-3

28.6

22.9

19.52

3.1

3.9

4.

HA-4

>30

>15

>90

ND

ND

5.

VC-1

4.1

2.76

12.39

3

4.5

6.

VC-2

23.6

20.9

42.2

1.7

2

7.

VC-3

15.9

13.5

19.52

1.2

1.4

8.

VC-4

>30

>15

>90

ND

ND

  1. Data were shown from three independent experiments
  2. Here, A: Schizont maturation Method [16]; B: pLDH method [17]; Cytotoxicity IC50 > 16 μg/ml; non cytotoxic