Table 1 Summary of World Health Organization (2010) and Government of Kenya (2005 and 2010) clinical practice guidelines for the management of children with severe malaria
Treatment for children aged < 5 years with a diagnosis of severe malaria | GoK 2005 Basic Paediatric Protocols* | GoK 2010 Malaria Case Management Guidelines | WHO 2010 Malaria Case Management Guidelines |
|---|---|---|---|
Pre-referral quinine loading dose | 15 mg/kg IM injection | 20 mg/kg IM injection | 20 mg/kg IM injection |
First-line treatment with quinine dose | 15 mg/kg loading dose then 10 mg/kg every 12 hours by IV infusion or divided IM injection | 20 mg/kg loading dose then 10 mg/kg every 8 hours by IV infusion or divided IM injection | 20 mg/kg loading dose then 10 mg/kg every 8 hours by IV infusion or divided IM injection |