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Table 3 Evidence quality and level of confidence in estimates using the GRADE approach

From: Treatment of African children with severe malaria - towards evidence-informed clinical practice using GRADE

Evidence Quality

Level of confidence in estimate

High

Further research is very unlikely to change our confidence in the estimate of effect

Moderate

Further research is likely to change our confidence in the estimate of effect, and may change the estimate

Low

Further research is very likely to change the estimate of effect, and is likely to change the estimate

Very low

The estimate of effect is very uncertain

  1. Adapted from Guyatt et al 2008 [26]
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Malaria Journal

ISSN: 1475-2875

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