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Table 3 Evidence quality and level of confidence in estimates using the GRADE approach

From: Treatment of African children with severe malaria - towards evidence-informed clinical practice using GRADE

Evidence Quality Level of confidence in estimate
High Further research is very unlikely to change our confidence in the estimate of effect
Moderate Further research is likely to change our confidence in the estimate of effect, and may change the estimate
Low Further research is very likely to change the estimate of effect, and is likely to change the estimate
Very low The estimate of effect is very uncertain
  1. Adapted from Guyatt et al 2008 [26]