Table 4 Characteristics of studies that evaluated quinine loading dose (Systematic review 1)
| Â | Â | Â | Test quinine sulphate dose (IV) | Comparator quinine sulphate dose (IV) | |
|---|---|---|---|---|---|
Study | Age range | Country | Loading dose | Maintenance dose | Uniform dose |
Assimadi 2002* (N = 72) | 8 months to 15 years | Benin | 21 mg/kg | 10.5 mg/kg every 12 hours | 15.9 mg/kg every 12 hours |
Fargier 1991* (N = 20) | 15 years and above | Cameroon | 19 mg/kg | 9.7 mg/kg every 8 hours | 9.7 mg/kg every 8 hours |
Pasvol 1991# (N = 59) | up to 12 years | Kenya | 20 mg/kg | 10 mg/kg every 12 hours | 5 to 10 mg/kg every 12 hours |
Tombe 1992 (N = 33) | 14 years and above | Kenya | 20 mg/kg | 10 mg/kg every 8 hours | 10 mg/kg every 8 hours |