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Table 2 Treatment outcomes after day 28 and 42

From: In vivo efficacy of artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria in Central Ethiopia

 

Duration of follow-up

Outcome

Day 28

Day 42

 

N = 119

N = 119

No treatment outcome

4 (3.4%)

7 (5.9%)

   Lost to follow-up

1

4

   Missed evening dose

3

3

Infection with different species

3 (2.5%)

8 (6.7%)

Failure

  

   Early Treatment Failure

0

0

   Late Clinical Failure

0

0

   Late Parasitological Failure

1

1

Adequate Clinical and Parasitological Response -uncorrected

111 (93.3%)

103 (86.6%)

Cure rates-Per Protocol, PCR uncorrected (95% CI)

99.1% (95.1-100.0)

99.0% (94.8-100.0)

Cure rates-Per Protocol, PCR corrected (95% CI)

100% (96.7-100.0)

100% (96.5-100.0)

Cure rates-Intention-to-treat, PCR uncorrected (95% CI)

93.3% (87.2-97.1)

86.6% (79.1-92.1)

Cure rates- Intention-to-treat, PCR corrected (95% CI)

94.1% (88.2-97.6)

87.3% (79.9-92.7)

  1. Abbreviations: CI- confidence interval