Figure 8

Proposed diagnostic algorithm. Model for how two different new test formats could be integrated into a uniform diagnostic regimen. Initial diagnosis would be made using a pan-specific test termed Pan-modium. If the test were positive, a second test to determine the species of malaria would be performed. This test, termed de-Linné-ate is comprised of 2 test strips (I and II) run in parallel. The de-Linné-ate strip contains the indicated antibodies and uniquely identifies each of the four human malaria parasite pLDH orthologs. Once an anti-malarial drug therapy has been initiated, progress towards clearing the malaria infection can followed using the all purpose Pan-modium strip.