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Table 3 Relationship between phenotype and genotype testing

From: Frequency of glucose-6-phosphate dehydrogenase deficiency in malaria patients from six African countries enrolled in two randomized anti-malarial clinical trials

G6PD genotype

G6PD phenotype

n/N (%)

Male A-

Deficient

70/99 (70.7)

 

Intermediate

19/99 (19.2)

 

Normal

10/99 (10.1)

Male A or B

Deficient

25/575 (4.3)

 

Intermediate

28/575 (4.9)

 

Normal

522/575 (90.8)

Female A-/A-

Deficient

12/25 (48.0)

 

Intermediate

7/25 (28.0)

 

Normal

6/25 (24.0)

Female A-/A or A-/B**

Deficient

13/174 (7.5)

 

Intermediate

33/174 (19.0)

 

Normal

128/174 (73.6)

Female AA, AB or BB

Deficient

14/446 (3.1)

 

Intermediate

40/446 (9.0)

 

Normal

392/446 (87.9)

  1. G6PD genotype: male hemizygous = A-; male normal = A or B; female homozygous = A-/A-; female heterozygous = A/A- or B/A-; and female normal = A/A, B/B or B/A
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Malaria Journal

ISSN: 1475-2875

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