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Table 3 Parasite carriage before and after the intervention

From: A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania

   

Asexual parasite carriage

Gametocyte carriage

   

microscope

QT-NASBA

microscope

QT-NASBA

2005

  

1.9 (1.4-2.5)

32.5 (28.2-37.0)

0.4 (0.2-0.7)

15.0 (11.9-18.7)

2008

Pre-intervention

Intervention

0.0 (0-2.1)

2.6 (0.3 - 9.2)

0.0 (0-2.1)

ND

  

Control

0.0 (0-1.7)

2.9 (0.04 - 10.1)

0.0 (0-1.7)

ND

 

Evaluation I

Intervention

0.0 (0-1.8)

0.0 (0.0 - 6.5)

0.0 (0-1.8)

ND

  

Control

0.0 (0-1.6)

0.0 (0.0 - 7.2)

0.0 (0-1.6)

ND

 

Evaluation II-IV

Intervention

0.0 (0-0.7)

0.0 (0.0 - 2.4

0.0 (0-0.7)

ND

  

Control

0.0 (0-0.5)

1.4 (0.2 - 5.1)

0.0 (0-0.5)

ND

  1. Asexual parasite carriage was determined by microscopy, reading 100 microscopic fields, and 18S rRNA-based QT-NASBA that detects all parasite stages at an estimated sensitivity of 20 parasites/mL. Gametocytes were detected by microscopy, separately reading 100 microscopic fields, and Pfs25 mRNA based QT-NASBA that is gametocyte specific and has a sensitivity of 20-100 gametocytes/mL. ND = not done
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Malaria Journal

ISSN: 1475-2875

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