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Table 2 Pfdhfr and pfdhps haplotypes of P.falciparum parasites from Luanda, Angola.

From: Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola

Gene

Haplotypes

n

%

Mutated codons

Pfdhfr

(n = 61)

CIRN

31

51

3

 

CI CN

21

34

2

 

CNRN

4

6

2

 

RI CN

4

6

3

 

CI C N/S

1

2

1 or 2

Pfdhps

(n = 30)

SG KAA

18

60

1

 

AG KAA

7

23

2

 

SAKAA

2

7

0

 

SGE AA

1

3

2

 

SGEG A

2

7

3

  1. Codon positions: pfdhfr C50R, N51I, C59R and S108N, pfdhps S436A/F/C, A437G, K540E, A581G and A613T/S. The sensitive haplotype is underlined and the mutated codons are shown in bold characters.
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Malaria Journal

ISSN: 1475-2875

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