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Table 2 Mapping of Overlapping Epitopes of the MSP4 EGF-like Domain

From: The antibody response to Plasmodium falciparum Merozoite Surface Protein 4: comparative assessment of specificity and growth inhibitory antibody activity to infection-acquired and immunization-induced epitopes

Competitor

Competition for Binding with Biotinylated Mab

Mab

4C10

1G10

7F4

8G3

1H2

6G11

4C10

+

+

-

-

-

+

1G10

+

+

-

-

-

+

7F4

-

-

+

+

-

-

8G3

-

-

+

+

-

-

1H2

+

+

-

-

+

+

6G11

-

-

-

-

-

+

  1. Mabs specific for rMSP4D analysed by pairwise competition ELISA.
  2. Inhibition (+) or no inhibition (-) of binding was observed.
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Malaria Journal

ISSN: 1475-2875

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