Skip to main content

Table 2 Geometric means of antibody titres as determined by ELISA.

From: Malaria infection by sporozoite challenge induces high functional antibody titres against blood stage antigens after a DNA prime, poxvirus boost vaccination strategy in Rhesus macaques

 

All PkAMA1

Protected PkAMA1

Not protected PkAMA1

All PkMSP119

Protected PkMSP119

Not protected PkMSP119

Post vaccination

2,305 [855-6,214]

2,417 [469-12,451]

2,137 [508-8,990]

332 [97-1,136]

633 [109-3,671]

118 [16-853]

Post challenge

79,030 [46,803-133,444]

94,870 [40,055-224,699]

59,000 [32,980-105,548]

16,784 [11,104-25,369]

17,875 [11,730-27,240]

15,175 [4,562-50,477]

  1. In brackets the 95% confidence intervals. No significant differences were observed between protected or not-protected groups of animals. For both antigens and all groups, antibody levels are significantly higher after challenge.