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Figure 3 | Malaria Journal

Figure 3

From: Transgenic Plasmodium parasites stably expressing Plasmodium vivax dihydrofolate reductase-thymidylate synthase as in vitro and in vivo models for antifolate screening

Figure 3

Sensitivity of transgenic Plasmodium falciparum expressing wild-type Pv DHFR-TS enzyme to pyrimethamine (A), chloroquine (B) and dihydroartemisinin (C). The growth of parasites treated with pyrimethamine, chloroquine and dihydroartemisinin was detected using the SYBR Green I staining assay. The percentage of parasite growth was plotted against drug concentrations. Data were shown as mean ± S.D. of at least 3 independent experiments. K1: P. falciparum K1CB1; TM4: P. falciparum TM4/8.2; B2: transgenic PfPvDTclB2.

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Malaria Journal

ISSN: 1475-2875

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