Figure 2From: Use of mefloquine in children - a review of dosage, pharmacokinetics and tolerability dataPlasma levels achieved during chemoprophylaxis in adult travellers. Data [52] showing plasma levels achieved during weekly prophylaxis in adult travellers, prior to travel in Africa and post travel. *Protective levels of mefloquine (620 ng/mL or 1.67 μmol/L) are achieved after two weeks of chemoprophylaxis dosing. The plasma profile in adults is similar to that in the simulated profile in children (Figure 1). MQ: mefloquine, MQ+, MQ-: mefloquine enantiomers, MMQ: carboxylic acid metabolite of mefloquineBack to article page