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Table 3 Distribution of ABO blood group in different clinical subtypes of severe falciparum infections and uncomplicated malaria

From: Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis

Blood group CM
(n=59)
MOD
(n=80)
NCSM
(n=108)
UM
(n=106)
CM vs UM
P value, OR
(95%CI)
MOD vs UM
P value, OR
(95%CI)
NCSM vs UM
P value, OR
(95%CI)
O 12 (20) 18 (22) 33 (31) 52 (49) ref ref ref
A 7 (12) 19 (24) 22 (20) 20 (19) 0.57, 0.65 (0.22 to 1.91) 0.02, 0.36 (0.15 to 0.83) 0.18, 0.57 (0.27 to 1.21)
B 33 (56) 40 (50) 46 (43) 24 (23) <0.0001, 5.95 (2.62 to 13.52) <0.0001, 4.81 (2.30 to 10.06) 0.001, 3.02 (1.56 to 5.83)
AB 7 (12) 3 (3) 7 (6) 10 (9) 0.10, 0.32 (0.10 to 1.04) 1.00, 1.15 (0.28 to 4.66) 1.00, 0.90 (0.31 to 2.61)
Non O (A+B+AB) 47 (80) 62 (78) 75 (69) 54 (51) 0.0003, 3.77 (1.80 to 7.90) 0.0002, 3.31 (1.73 to 6.34) 0.0078, 2.81 (1.25 to 3.82)
  1. NOTE: Data are no. (%) of participants unless otherwise specified.
  2. CM: cerebral malaria; MOD: multi-organ dysfunction; NCSM: non-cerebral severe malaria; UM: uncomplicated malaria; OR: odds ratio; CI: confidence interval