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Table 1 The nucleotide and amino acid substitutions at dhfr gene screened for by PCR-SSOP

From: The evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination

Codon 50 51 59 108 164
Wild type Cys (C)
TGT
Asn (N)
AAT
AAC
Cys (C)
TGT
Ser (S) AGC Ile (I)
ATA
Mutant Arg (R)
CGT
Ile (I)
ATT
Arg (R)
CGT
Asn (N) AAC
Thr (T)
ACC
Leu (L)
TTA