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Figure 9 | Malaria Journal

Figure 9

From: Systematic review and meta-analysis: rapid diagnostic tests versus placental histology, microscopy and PCR for malaria in pregnant women

Figure 9

Summary ROC plot of sensitivity and specificity of RDT and PCR of peripheral and placental blood and microscopy of peripheral blood with placental blood microscopy as reference test. The sensitivity of a certain test is plotted against 1-specificity, allowing comparison of both parameters at the same time for multiple tests. The squares, diamonds and open circles represent individual studies and size of the rectangles/diamonds/circles is proportional to the number of patients included in the study. The thick round spots are the summary estimates of sensitivity and specificity and the dotted ellipses around the spots represent the 95% confidence intervals around the summary estimates. Black (squares): RDTs (detecting HRP2 or pLDH or HRP2-Aldolase). Red (diamonds): peripheral blood microscopy. Green (circles): PCR; The reference test used to determine the plotted accuracies in this figure is placental blood microscopy.

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