Figure 2
From: Evaluation of immunity against malaria using luciferase-expressing Plasmodium berghei parasites
Real-time in vivo parasite liver load upon challenge in mice immunized with CPS or RAS. (A) Image (2 representative mice for each group) of the parasite liver load in control (n = 10), CPS (n = 10) and RAS immunized (n = 10) C57BL/6 mice 44 hours post challenge. Mice were immunized i.v with 1 × 104 sporozoites followed by two boosts of 1 × 104 sporozoites. Challenge was performed by infectious mosquito bites. The rainbow image visible in the naive mice represents the total flux of photons (p/sec/cm2) in that area. (B) Image (2 control mice and 3 immunized mice) of the parasite liver load in control (n = 3) and CPS immunized (n = 5) C57BL/6 mice 30-45 hours post challenge. Mice were immunized with 4 × 103 sporozoites by i.v injection followed by two boosts of 4 × 103 sporozoites. Challenge was performed by injection of 1 × 104 Pb GFP-Luc con sporozoites i.v. The rainbow image visible in the control mice represents the total flux of photons (p/sec/cm2) in that area.