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Table 4 Impact of interventions on anaemia prevalence at the end of the transmission season

From: Impact of combining intermittent preventive treatment with home management of malaria in children less than 10 years in a rural area of Senegal: a cluster randomized trial

Anaemia (Hb inf 11 g/dl)

 

Participants (%)

OR (95% CI)

aOR (95% CI)

Protective efficacy (%) 95% CI

p value

Interventions

     

HMM (n = 411)

248 (60.3)

1

1

  

HMM+IPTc (n = 438)

237 (54.1)

0.77[0.59 -1.02]

0.59[0.37-0.93]

41%[18;58]

0.025

Gender

     

Female (n = 398)

213 (53.5)

1

1

  

Male (451)

272(60.3)

1.32[1.01-1.73]

1.19[0.80-1.75]

-19%[-75;20]

0.35

P. falciparum carriage

     

No (n = 821)

464 (56.5)

1

1

  

Yes (n = 28)

21 (75.0)

2.30[0.83-6.37]

2.56[1.12-5.85]

-156%[-485;-12]

0.026

Stunting (HAZ < -2SD)

     

No (n = 546)

265 (48.53)

1

1

  

Yes (n = 305)

220 (72.13)

2.72 [1.86-3.98]

2.97[2.41-3.66]

-197[-323;-108]

0.001

Age groups

     

Under 2 years n = 179)

162 (90.5)

1

1

  

[2-5 years](n = 374)

233 (62.30)

0.17[0.09-0.31]

0.14[0.08-0.24]

86%[76;92]

0.001

[5-10 years] (n = 296)

88 (29.73)

0.04[0.02-0.08]

0.04[0.02-0.07]

96%[93;98]

0.001

  1. Goodness of fit test: Hosmer Lemeshow, Chi 2 (8df) = 7,36, p = 0,49. *aOR adjusted odds ratio; OR odds ratio. Intra-class correlation coefficients for each outcome were as follows: age:0.02, Gender:0.001, stunting:0.08, slide microscopy positive:0.011. All p values are adjusted for clustering by robust standard errors.