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Figure 4 | Malaria Journal

Figure 4

From: Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins

Figure 4

Summary of the cross reactivity observed per DBL domain across parasite panel. The top row in each box shows the DBL domain used for immunization. On the left is listed the VAR2CSA allelic variant and animal species immunized. Mean fluorescence intensities in flow cytometry are shown as a heat map from yellow (lower) to red (higher). Rat plasma were analysed at 1/20 dilution and rabbit plasma at 1/25 dilution. Previously published observations are indicated with superscripts: 1[30] and 2[29]. All plasma were tested against the individual HB3A and HB3B CSA-binding parasite lines except the previously published rabbit anti-IT4 DBL5 and anti-IT4 DBL6 were examined against a mixed HB3-CSA parasite line.

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