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Table 1 Restriction enzymes and result of genetic polymorphisms of G6PD mutation variants

From: Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand

G6PD Variant

cDNA

Nucleotide

Substitution

Amino acid Substitution

Restriction enzyme

Results (bp)

Gaohe

95 A > G

32 His > Arg

Mlu I

N 198, M 174+24

Chinese 4

392 G > T

131 Gly > Val

BstE II

N 188+15, M 203

Mahidol

487 G > A

163 Gly > Ser

Hind III

N 104, M 82+22

Chinese 3

493 A > G

165 Asn > Asp

Ava II

N 120+11, M 87+33+11

Coimbra

592 C > T

198 Arg > Cys

Pst I

N 157+83, M 157+63+20

Viangchan

871 G > A

291 Val > Met

Xb aI

N 126, M 106+20

Chinese5

1024 C > T

342 Leu > Phe

Mbo II

N 187, M 150+37

Union

1360 C > T

454 Arg > Cys

Hha I

N 142+45+27, M 187+27

Canton

1376 C > T

459 Arg > Leu

Afl II

N 214, M 194+20

Kaiping

1388 G > A

463 Arg > His

Nde I

N 227, M 206+21

  1. N normal digestion result
  2. M mutant digestion result