Table 2 Baseline characteristics (safety population)
Baseline Characteristics | Body weight | |||
|---|---|---|---|---|
5 to < 10 kg (n = 168) | 10 to < 15 kg (n = 379) | 15 to < 25 kg (n = 289) | 25 to < 35 kg (n = 63) | |
Body weight (kg) | ||||
Mean(SD) | 8.3 (1.1) | 12.1 (1.4) | 18.1 (2.6) | 28.1 (3.0) |
Median (range) | 8.5 (5.0-9.9) | 12.0 (10.0-14.7) | 17.8 (15.0-24.5) | 27.0 (25.0-34.0) |
Female gender, n (%) | 86 (51.2) | 182 (48.0) | 136 (47.1) | 16 (25.4) |
Age, months | ||||
Mean (SD) | 14.4 (6.7) | 35.9 (13.5) | 71.7 (22.4) | 119.3 (20.5) |
Median (range) | 14 (0.0-42)a | 35 (6-70) | 71 (31-148) | 122 (78-152) |
Temperature,°C | ||||
Mean (SD) | 37.9 (1.2) | 38.1 (1.1) | 37.9 (1.0) | 38.0 (1.0) |
Parasite density, /μL | ||||
Mean (SD) | 49,571 (51,536) | 53,921 (57,572) | 40,974 (41,763) | 21,850 (24,867) |
Median (range) | 31,937 | 35,400 | 26,640 | 13,040 |
(0-228,000) | (520-628,571) | (2,039-192,610) | (1,581-109,720) | |