Efficacy outcomes | Body weight | |||
---|---|---|---|---|
5 to < 10 kg | 10 to < 15 kg | 15 to < 25 kg | 25 to < 35 kg | |
14-day PCR curea | ||||
n/N | 140/143 | 334/334 | 277/277 | 58/58 |
% | 97.9 | 100.0 | 100.0 | 100.0 |
95% CI (%) | 94.0-99.6 | 97.9-100.0 | 98.7-100.0 | 90.8-100.0 |
28-day PCR curea | ||||
n/N | 139/143 | 330/334 | 271/277 | 57/58 |
% | 97.2% | 98.8% | 97.8% | 98.3% |
95% CI (%) | 93.0-99.2% | 97.0-99.7% | 95.3-99.2% | 90-8-100.0% |
42-day PCR curea | ||||
n/N | 123/129 | 284/290 | 227/237 | 50/53 |
% | 95.3 | 97.9 | 95.8 | 94.3 |
95% | 90.2-98.3 | 95.6-99.2 | 92.4-98.0 | 84.3-98.8 |
Kaplan Meier estimates of parasite clearance time, hb | ||||
N | 164 | 371 | 288 | 63 |
Median | 35.6 | 35.0 | 25.8 | 25.8 |
Interquartile range | 24.0-36.1 | 23.9-36.1 | 23.8-35.9 | 23.9-35.7 |
Mean (SE) | 35.0 (1.2) | 32.8 (1.0) | 31.7 (1.1) | 30.8 (1.6) |
Kaplan Meier estimates of fever clearance time, hb | ||||
N | 164 | 369 | 288 | 63 |
Median | 8.2 | 7.8 | 7.8 | 7.7 |
Interquartile range | 7.7-35.0 | 7.5-23.6 | 7.6-23.4 | 7.4-8.5 |
Mean (SE) | 44.4 (9.1) | 26.5 (3.5) | 30.5 (6.4) | 11.5 (1.4) |