Table 1 In vitro susceptibility and Pfnhe-1 polymorphisms of the 74 Plasmodium falciparum isolates from the Republic of Congo
Isolates | Cpm without drug | Cpm With highest QN concentration | QN IC50 | No DNNND repeat | No NHNDNHNNDDD repeat | No genotype profile |
|---|---|---|---|---|---|---|
16517 | 23404 | 1440 | 1097 | 3 | 2 | ms4760-27 |
16612 | 49650 | 8273 | 888 | 1 | 2 | ms4760-3 |
16520 | 6512 | 1077 | 882 | 1 | 2 | ms4760-3 |
16094 | 2007 | 620 | 862 | 2 | 1 | ms4760-24 |
16980 | 2151 | 980 | 782 | 2 | 2 | ms4760-33 |
17267 | 2558 | 455 | 776 | 2 | 2 | ms4760-1 |
16631 | 1807 | 282 | 750 | 1 | 2 | ms4760-3 |
16698 | 1263 | 353 | 740 | 2 | 1 | ms4760-6 |
16960 | 2011 | 714 | 689 | 2 | 2 | ms4760-1 |
16958 | 19732 | 861 | 645 | 3 | 2 | ms4760-30 |
16983 | 3710 | 943 | 627 | 3 | 2 | ms4760-1 |
16957 | 19773 | 1300 | 615 | 1 | 2 | ms4760-29 |
16966 | 2264 | 545 | 604 | 2 | 2 | ms4760-31 |
16941 | 18540 | 1175 | 576 | 1 | 2 | ms4760-3 |
16991 | 2804 | 815 | 567 | 1 | 1 | ms4760-36 |
16953 | 5675 | 1249 | 564 | 1 | 2 | ms4760-12 |
16539 | 44532 | 4112 | 537 | 1 | 2 | ms4760-3 |
17250 | 6558 | 606 | 506 | 1 | 2 | ms4760-3 |
16942 | 10927 | 1163 | 502 | 1 | 2 | ms4760-3 |
16959 | 9886 | 914 | 488 | 2 | 2 | ms4760-1 |
17008 | 2151 | 961 | 482 | 1 | 2 | ms4760-35 |
16986 | 2302 | 624 | 481 | 2 | 2 | ms4760-1 |
16968 | 8477 | 962 | 457 | 2 | 2 | ms4760-1 |
17249 | 1276 | 412 | 408 | 1 | 2 | ms4760-22 |
17216 | 3179 | 539 | 404 | 1 | 2 | ms4760-38 |
17253 | 9717 | 1091 | 396 | 2 | 1 | ms4760-6 |
16987 | 7232 | 938 | 388 | 3 | 1 | ms4760-15 |
16349 | 28606 | 2048 | 377 | 3 | 1 | ms4760-25 |
17231 | 3545 | 389 | 354 | 1 | 2 | ms4760-39 |
16518 | 8912 | 1361 | 351 | 3 | 1 | ms4760-7 |
16955 | 9379 | 1188 | 346 | 3 | 2 | ms4760-27 |
17211 | 6451 | 655 | 346 | 1 | 2 | ms4760-3 |
16695 | 27421 | 2316 | 341 | 1 | 2 | ms4760-3 |
16996 | 1347 | 597 | 340 | 2 | 2 | ms4760-34 |
17208 | 18356 | 1208 | 335 | 1 | 2 | ms4760-3 |
16536 | 6617 | 847 | 333 | 2 | 2 | ms4760-1 |
16365 | 4631 | 724 | 332 | 1 | 2 | ms4760-22 |
16979 | 7449 | 990 | 326 | 2 | 2 | ms4760-18 |
17202 | 11053 | 929 | 319 | 1 | 2 | ms4760-3 |
16364 | 12210 | 1990 | 316 | 2 | 2 | ms4760-26 |
16331 | 8912 | 1113 | 314 | 3 | 2 | ms4760-9 |
15868 | 1530 | 498 | 309 | 1 | 2 | ms4760-22 |
16610 | 4063 | 961 | 305 | 3 | 1 | ms4760-7 |
16535 | 16007 | 1274 | 291 | 3 | 1 | ms4760-15 |
16323 | 43074 | 5859 | 290 | 1 | 2 | ms4760-12 |
16992 | 9464 | 1111 | 276 | 1 | 2 | ms4760-12 |
17237 | 12385 | 873 | 269 | 1 | 2 | ms4760-3 |
17305 | 21667 | 1398 | 269 | 2 | 2 | ms4760-3 |
16305 | 11269 | 917 | 265 | 1 | 2 | ms4760-3 |
17303 | 18553 | 1646 | 264 | 2 | 2 | ms4760-1 |
17212 | 2755 | 520 | 259 | 1 | 2 | ms4760-3 |
16304 | 16194 | 738 | 254 | 2 | 2 | ms4760-1 |
17241 | 5758 | 447 | 254 | 1 | 2 | ms4760-3 |
16970 | 2359 | 705 | 247 | 1 | 1 | ms4760-32 |
16995 | 7642 | 1004 | 247 | 2 | 2 | ms4760-1 |
17210 | 11018 | 1370 | 244 | 1 | 2 | ms4760-22 |
17233 | 12100 | 956 | 231 | 2 | 1 | ms4760-6 |
17265 | 1593 | 238 | 226 | 2 | 2 | ms4760-1 |
17214 | 2421 | 316 | 224 | 2 | 2 | ms4760-37 |
17209 | 3499 | 680 | 216 | 3 | 2 | ms4760-9 |
17007 | 3633 | 1159 | 212 | 3 | 2 | ms4760-9 |
16116 | 11417 | 999 | 204 | 2 | 2 | ms4760-18 |
17201 | 25594 | 2530 | 204 | 1 | 1 | ms4760-36 |
17304 | 24453 | 1982 | 199 | 2 | 2 | ms4760-1 |
16086 | 10918 | 699 | 174 | 3 | 1 | ms4760-15 |
17283 | 4391 | 315 | 146 | 3 | 2 | ms4760-1 |
17010 | 2897 | 1103 | 141 | 3 | 2 | ms4760-9 |
16117 | 17474 | 1291 | 121 | 2 | 2 | ms4760-1 |
16078 | 1654 | 396 | 106 | 2 | 2 | ms4760-1 |
16085 | 5229 | 707 | 86 | 2 | 1 | ms4760-6 |
17301 | 39337 | 2016 | 84 | 1 | 2 | ms4760-12 |
15867 | 6893 | 739 | 73 | 1 | 2 | ms4760-3 |
16091 | 17320 | 1695 | 67 | 2 | 2 | ms4760-1 |
16077 | 4539 | 353 | 36 | 1 | 2 | ms4760-23 |