Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi

Table 1 Matching of six P. malariae microsatellite loci to P. falciparum microsatellite loci by expected heterozygosity (H_E) and number of alleles detected

	All data		Dominant only			All data		Dominant only
P. malariae locus	H_E	Number of alleles	H_E	Number of alleles	P. falciparum locus	H_E	Number of alleles	H_E	Number of alleles
Pm09	0.276	11	0.192	8	TAA42	0.551	14	0.442	13
Pm11	0.480	9	0.395	8	377	0.679	10	0.587	8
Pm47	0.516	5	0.471	5	TAA60	0.811	15	0.794	13
Pm34	0.587	13	0.526	11	TAA109	0.841	19	0.820	15
Pm25	0.758	14	0.729	11	TAA81	0.840	13	0.830	10
Pm02	0.862	13	0.849	12	ARA2	0.871	14	0.853	13
					TA1	0.805	29	0.678	25
					2490	0.868	11	0.863	11
					TAA87	0.877	18	0.873	15
					PK2	0.892	19	0.887	17
					Polyα	0.908	21	0.911	19

H_E values were calculated for all alleles detected, including those from samples with multiple alleles per locus (all data) and from a restricted data set in which only the dominant allele at each locus was used (dominant only). One out of the 12 published P. falciparum loci (TA40) [27] was not used as this was found not to amplify.

ISSN: 1475-2875