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Table 6 Multi-locus linkage analysis of P. malariae and P. falciparum haplotypes

From: Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi

  

All data

Unique haplotypes

  

IAS

p-value

IAS

p-value

P. malariae

Both Districts

-0.003

0.650

-0.022

0.994

 

Dedza

-0.009

0.765

-0.026

0.986

 

Mangochi

-0.003

0.575

-0.032

0.992

P. falciparum

Both Districts

0.012

< 0.05

0.009

< 0.05

 

Dedza

0.016

< 0.05

0.012

0.055

 

Mangochi

0.007

0.181

0.004

0.304

  1. The standardized index of association (I A S) measures linkage disequilibrium by comparing the variance in the number of shared alleles between all pairs of haplotypes with the variance within the randomized data. Unique haplotypes are a subset of the data, in which haplotypes found in more than one sample are represented only once. P. malariae, all data: Dedza n = 108, Mangochi n = 59; unique haplotypes: Dedza n = 81, Mangochi n = 35. P. falciparum, all data: Dedza n = 108, Mangochi n = 92; unique haplotypes: Dedza n = 106, Mangochi n = 87.