Figure 5

A Representative OPLS-DA loadings S-plot showing relative contribution of bins/spectral variables to clustering of Plasmodium vivax- infected patients and healthy individuals. This plot corresponds to Figure 2. Each point in the figure represents a bin. The p(corr)[1] axis represents the correlation of the bin towards the predictive variation shown in Figure 1. The p[1] axis represents the magnitude of the spectral bins. Bins from region circled in red represents the bins that decreased in the P. vivax infected individuals. Bins from region circled in black represents the bins that increased in the P. vivax infected individuals. Among them, bins with high p(corr)[1] (< -0.2 for increased and > 0.5 for decreased), high p[1] and VIP above cut-off (listed in Table 1) are selected for further analysis.