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Table 1 Biological functions perturbed following hyperoxia exposure on P. falciparum

From: Global response of Plasmodium falciparum to hyperoxia: a combined transcriptomic and proteomic approach

Functional groupa Number of entitiesb p-valuec
GPI anchor biosynthesis 29 0.0006
DNA repair 15 0.0072
Vacuolar acidification 11 0.0255
Actin filament organization 12 0.0296
Nucleosome assembly 12 0.0490
Regulation of cell shape 6 0.0519
Leading strand elongation 10 0.0533
Lysosomal H+ import 26 0.0589
Response to oxidative stress 17 0.0799
  1. aGene Set Enrichment Analysis (GSEA) using the Mann-Whitney-U-test enrichment algorithm in PathwayStudio software indicated functional groups significantly altered (p < 0.08). For each functional group, the bnumber of genes included and corresponding cp-values are listed.