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Table 2 Sensitivity of P. vivax to chloroquine and WR99120; data are presented as geometric mean and median (95%CI) values of IC10, IC50 and IC90 obtained from 32 isolates.

From: Monitoring of clinical efficacy and in vitro sensitivity of Plasmodium vivax to chloroquine in area along Thai Myanmar border during 2009-2010

Drugs

Inhibitory Concentration (IC)

Geometric mean (nM)

Median (range) (nM)

Chloroquine

IC10

3.3

4.2 (0.2-7.1)

 

IC50

100.1

134.7 (1.1-264.9)

 

IC90

2956.5

4134.9 (7.1-11535.0)

WR99210

IC10

4.9

5.7 (0.04-17.8)

 

IC50

112.7

139.9 (0.2-523.0)

 

IC90

2585.0

3406.9 (1.1-15356.0)

  1. IC 10, 50 and 90: drug concentrations which produced 10, 50 and 90% inhibition of parasite development, respectively, as compared to the control (analysed by nonlinear regression analysis using CalcuSynâ„¢software).