Table 1 Demographic characteristics on admission of women with Plasmodium falciparum infection (pregnant cases and non-pregnant controls)
| Â | Pregnant cases | Â | Â | |||
|---|---|---|---|---|---|---|
Characteristic | Window 1 (22-26 wks GA) | Window 2 (32-36 wks GA) | P-value* | All | Non-pregnant controls | P-value†|
N | 13 | 13 | Â | 26 | 25 | Â |
Age (years)‡ | 21.7 ± 2.7 | 26.6 ± 4.4 | 0.0065 | 24.2 ± 4.4 | 24.8 ± 5.5 | 0.79 |
Height (m)‡ | 1.6 ± 0.1 | 1.6 ± 0.1 | 0.56 | 1.6 ± 0.1 | 1.6 ± 0.1 | 0.77 |
Weight (kg)‡ | 55.5 ± 8.3 | 63.0 ± 7.2 | -- | -- | 55.2 ± 10.6 | -- |
Postpartum (3 months) weight (kg)‡ | 53.7 ± 7.6 | 58.0 ± 4.3 | 0.14 | 55.8 ± 6.4 |  | 0.29 |
BMI (kg/m2)‡ | 21.2 ± 2.8 | 24.4 ± 2.2 | -- | 22.7 ± 3.0 | 21.0 ± 3.2 | 0.055 |
Postpartum (3 months) BMI (kg/m2)‡ | 20.3 ± 2.3 | 22.6 ± 1.7 | 0.017 | 21.4 ± 2.3 |  | 0.29 |
Education (years)‡ | 9.0 ± 3.6 | 9.5 ± 3.0 | 0.57 | 9.2 ± 3.3 | 9.8 ± 3.8 | 0.73 |
Parity§ | 0 (0 - 2) | 1 (0 - 4) | 0.081 | 1 (0 - 4) | 0 (0 - 4) | 0.0013 |
Parity | Â | Â | 0.23 | Â | Â | 0.0002 |
   0 | 7 (53.8) | 4 (30.8) |  | 11 (42.3) | 23 (92.0) |  |
   1 | 5 (38.5) | 3 (23.1) |  | 8 (30.8) | 0 (0.0) |  |
   2 | 1 (7.7) | 4 (30.8) |  | 5 (19.2) | 1 (4.0) |  |
   3-4 | 0 (0.0) | 2 (15.4) |  | 2 (7.7) | 1 (4.0) |  |
GA at ultrasound screening (weeks)‡ | 18.9 ± 1.5 | 18.5 ± 1.5 | 0.41 | -- | -- | -- |
GA at study screening (weeks)‡ | 22.4 ± 0.8 | 33.2 ± 1.4 | -- | -- | -- | -- |
Body temperature (°C)║ | 36.5 (36.1 - 36.7) | 36.4 (36.2 - 36.5) | 0.66 | 36.5 (36.1 - 36.6) | 36.6 (36.4 - 36.8) | 0.044 |
Haematocrit (%)â•‘ | 30.0 (30.0 - 30.0) | 32.0 (31.0 - 33.0) | 0.035 | 30.5 (30.0 - 33.0) | 38.0 (34.0 - 38.0) | <.0001 |
Dosage (mg/kg) â•‘ | 3.45 (3.17-4.17) | 3.08 (2.99-3.17) | 0.017 | 3.17 (3.08-4.00) | 3.86 (3.39-4.17) | 0.061 |