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Table 3 PCR-adjusted and unadjusted treatment outcomes by days 28 and 42

From: Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children

 

DHA/PQP (N = 192) n (%)

AL (N = 90) n (%)

Odds Ratio (95% CI)

p-value

PCR-unadjusted

    

Day 28

    

LCF

6 (3.1)

10 (11.1)

0.26 (0.08-0.80)

0.007

LPF

9 (4.7)

13 (14.4)

0.29 (0.11-0.77)

0.004

ACPR

177 (92.2)

67 (74.4)

4.05 (1.89-8.74)

<<0.001

Day 42

    

LCF

11 (5.8)

13 (14.4)

0.36 (0.41-0.90)

0.014

LPF

31 (16.1)

20 (22.2)

0.67 (0.34-1.32)

0.217

ACPR

150 (78.1)

57 (63.3)

2.07 (1.15-3.71)

0.009

PCR-adjusted

    

Day 28

    

LCF

0 (0)

3 (3.3)

  

LPF

9 (4.7)

3 (3.3)

  

ACPR

183 (95.3)

84 (93.3)

1.45 (0.44-4.64)

0.33*

Day 42

    

LCF

4(2.1)

3(3.3)

  

LPF

9(4.7)

3(3.3)

  

ACPR

179 (93.2)

84 (93.3)

0.98 (0.32-2.90)

0.974

  1. *Fisher exact p values