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Table 3 PCR-adjusted and unadjusted treatment outcomes by days 28 and 42

From: Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children

  DHA/PQP (N = 192) n (%) AL (N = 90) n (%) Odds Ratio (95% CI) p-value
PCR-unadjusted     
Day 28     
LCF 6 (3.1) 10 (11.1) 0.26 (0.08-0.80) 0.007
LPF 9 (4.7) 13 (14.4) 0.29 (0.11-0.77) 0.004
ACPR 177 (92.2) 67 (74.4) 4.05 (1.89-8.74) <<0.001
Day 42     
LCF 11 (5.8) 13 (14.4) 0.36 (0.41-0.90) 0.014
LPF 31 (16.1) 20 (22.2) 0.67 (0.34-1.32) 0.217
ACPR 150 (78.1) 57 (63.3) 2.07 (1.15-3.71) 0.009
PCR-adjusted     
Day 28     
LCF 0 (0) 3 (3.3)   
LPF 9 (4.7) 3 (3.3)   
ACPR 183 (95.3) 84 (93.3) 1.45 (0.44-4.64) 0.33*
Day 42     
LCF 4(2.1) 3(3.3)   
LPF 9(4.7) 3(3.3)   
ACPR 179 (93.2) 84 (93.3) 0.98 (0.32-2.90) 0.974
  1. *Fisher exact p values