Figure 2
From: Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage
Atorvastatin decreasing effect on P. falciparum endothelial cytoadherence: HLECs were pre-treated with various doses of atorvastatin ((0.01, 0.025, 0.05, 0.1, 0.5, 1 microM)) for 24 hours before addition of RBCs or PRBCs at a haematocrit of 5% and a parasitemia of 50% for 1 hour. After removal of unbound erythrocytes, cells were stained with Giemsa and the number of adhered pRBC to 700 HLEC was counted. Data are the mean ±SD of pRBC cytodherence (n = 4), **P < 0.01.